MolNFT v1 · #29390 · protein

Crystal structure of transcriptional regulator protein from thermotoga maritima.

1Z77 · Transcriptional regulator (tetr family): “Crystal structure of transcriptional regulator protein from thermotoga maritima.”. X-ray diffraction, 2 pockets (best druggability 0.76). MolNFT v1 #29390 on GenesisL1: 3D structure, binding…

PDB: 1Z77
Type: protein
Length: 200 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator (tetr family)
UniProt: Q9X0C0
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 81% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator (tetr family)	protein	200	81% helix, 1% strand	Q9X0C0

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 2 copies

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	476	0.76	0.84	39	empty
2	55	0.26	0.73	14	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

1Z77 · Crystal structure of transcriptional regulator protein from Thermotoga maritima. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X0C0
Elsewhere: RCSB PDB 1Z77 · PDBe 1Z77 · UniProt Q9X0C0

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