MolNFT v1 · #29363 · protein

Crystal structure of guanylate kinase from plasmodium falciparum

1Z6G: “Crystal structure of guanylate kinase from plasmodium falciparum”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.67). MolNFT v1 #29363 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1Z6G
Type: protein
Length: 191 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Guanylate kinase
EC: 2.7.4.8
UniProt: Q8I2M1
Ligands: SO4
Pockets: 1 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Guanylate kinase (EC 2.7.4.8)	protein	191	42% helix, 22% strand	Q8I2M1

Ligands and binding sites

SO4 · Sulfate ion · ion · 5 copies · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	473	0.67	0.78	38	SO4, EPE

Compared structures

1Z6G · Crystal structure of guanylate kinase from Plasmodium falciparum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8I2M1
Elsewhere: RCSB PDB 1Z6G · PDBe 1Z6G · UniProt Q8I2M1

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