MolNFT v1 · #29231 · protein
Structure of pyrococcus furiosus argonaute with bound tungstate
1Z26: “Structure of pyrococcus furiosus argonaute with bound tungstate”. X-ray diffraction, 1 ligand (WO4), 9 pockets (best druggability 0.74). MolNFT v1 #29231 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1Z26
- Type
- protein
- Length
- 716 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Argonaute
- UniProt
- Q8U3D2
- Ligands
- WO4
- Pockets
- 9 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Argonaute | protein | 716 | 32% helix, 29% strand | Q8U3D2 |
Ligands and binding sites
- WO4 · Tungstate(vi)ion · ion · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 680 | 0.74 | 0.80 | 77 | empty |
| 2 | 281 | 0.53 | 0.75 | 25 | empty |
| 3 | 170 | 0.52 | 0.79 | 32 | empty |
| 4 | 190 | 0.47 | 0.75 | 28 | empty |
| 5 | 146 | 0.46 | 0.76 | 22 | empty |
Compared structures
- 1Z26 · Structure of Pyrococcus furiosus Argonaute with bound tungstate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8U3D2
- Elsewhere: RCSB PDB 1Z26 · PDBe 1Z26 · UniProt Q8U3D2
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