MolNFT v1 · #29188 · protein
Crystal structure of a. fulgidus lon proteolytic domain
1Z0T · Putative protease la homolog type: “Crystal structure of a. fulgidus lon proteolytic domain”. X-ray diffraction, 20 pockets (best druggability 0.68). MolNFT v1 #29188 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1Z0T
- Type
- protein
- Length
- 1,174 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative protease la homolog type
- EC
- 3.4.21.53
- UniProt
- O29883
- Pockets
- 20 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | Putative protease la homolog type (EC 3.4.21.53) | protein | 195 | 32% helix, 30% strand | O29883 |
| B, C, D, F | Putative protease la homolog type (EC 3.4.21.53) | protein | 196 | 32% helix, 27% strand | O29883 |
Pockets
20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 429 | 0.68 | 0.80 | 52 | empty |
| 2 | 384 | 0.67 | 0.80 | 46 | empty |
| 3 | 102 | 0.62 | 0.88 | 26 | empty |
| 4 | 314 | 0.61 | 0.78 | 44 | empty |
| 5 | 95 | 0.59 | 0.87 | 23 | empty |
Interfaces
6 interfaces between chains.
- C–D · 963 Ų buried · 16 hydrogen bonds · protein-protein
- A–F · 945 Ų buried · 17 hydrogen bonds · protein-protein
- D–E · 930 Ų buried · 19 hydrogen bonds · protein-protein
- A–B · 885 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 803 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O29883
- Elsewhere: RCSB PDB 1Z0T · PDBe 1Z0T · UniProt O29883
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.