MolNFT v1 · #29071 · protein
SERPINA3N, a murine orthologue of human antichymotrypsin
1YXA · Serine (or cysteine) proteinase inhibitor, clade a, member…: “SERPINA3N, a murine orthologue of human antichymotrypsin”. X-ray diffraction, 7 pockets (best druggability 0.45). MolNFT v1 #29071 on GenesisL1: 3D structure, binding…
- PDB
- 1YXA
- Type
- protein
- Length
- 740 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serine (or cysteine) proteinase inhibitor, clade a, member 3N
- UniProt
- Q91WP6
- Pockets
- 7 · best druggability 0.45
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine (or cysteine) proteinase inhibitor, clade a, member 3N | protein | 372 | 30% helix, 31% strand | Q91WP6 |
| B | Serine (or cysteine) proteinase inhibitor, clade a, member 3N | protein | 368 | 31% helix, 31% strand | Q91WP6 |
Pockets
7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.45 | 0.85 | 16 | empty |
| 2 | 93 | 0.43 | 0.79 | 24 | empty |
| 3 | 86 | 0.36 | 0.76 | 18 | empty |
| 4 | 95 | 0.34 | 0.74 | 14 | empty |
| 5 | 61 | 0.32 | 0.76 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 185 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91WP6
- Elsewhere: RCSB PDB 1YXA · PDBe 1YXA · UniProt Q91WP6
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