MolNFT v1 · #2903 · protein
Determination of three crystal structures of canavalin by molecular replacement
1CAX: “Determination of three crystal structures of canavalin by molecular replacement”. X-ray diffraction, 16 pockets (best druggability 0.80). MolNFT v1 #2903 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1CAX
- Type
- protein
- Length
- 1,095 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Canavalin
- UniProt
- P50477
- Pockets
- 16 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 12% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E | Canavalin | protein | 181 | 12% helix, 41% strand | P50477 |
| B, D, F | Canavalin | protein | 184 | 13% helix, 41% strand | P50477 |
Pockets
16 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 136 | 0.80 | 0.97 | 26 | empty |
| 2 | 187 | 0.78 | 0.93 | 36 | empty |
| 3 | 106 | 0.77 | 0.97 | 25 | empty |
| 4 | 74 | 0.76 | 0.99 | 20 | empty |
| 5 | 67 | 0.75 | 0.99 | 19 | empty |
Interfaces
9 interfaces between chains.
- C–F · 2931 Ų buried · 33 hydrogen bonds · protein-protein
- B–E · 2886 Ų buried · 35 hydrogen bonds · protein-protein
- A–D · 2821 Ų buried · 33 hydrogen bonds · protein-protein
- C–D · 1738 Ų buried · 17 hydrogen bonds · protein-protein
- E–F · 1646 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 1CAX · Determination of three crystal structures of canavalin by molecular replacement · the same entry in another collection · chain F against F, TM-score 1.00
- P50477 · AlphaFold monomer V2.0 prediction for canavalin (P50477) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50477
- Elsewhere: RCSB PDB 1CAX · PDBe 1CAX · UniProt P50477
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.