MolNFT v1 · #28932 · protein

Crystal structure of thiosulfate sulfurtransferase from pseudomonas aeruginosa

1YT8: “Crystal structure of thiosulfate sulfurtransferase from pseudomonas aeruginosa”. X-ray diffraction, 1 ligand (SO3), 4 pockets (best druggability 0.63). MolNFT v1 #28932 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YT8
Type: protein
Length: 525 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thiosulfate sulfurtransferase
EC: 2.8.1.1
UniProt: Q9I0N4
Ligands: SO3
Pockets: 4 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thiosulfate sulfurtransferase (EC 2.8.1.1)	protein	525	43% helix, 16% strand	Q9I0N4

Ligands and binding sites

SO3 · Sulfite ion · ion · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	520	0.63	0.76	65	GOL
2	135	0.46	0.77	20	empty
3	79	0.37	0.77	16	empty
4	65	0.29	0.73	12	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

1YT8 · Crystal Structure of Thiosulfate sulfurtransferase from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I0N4
Elsewhere: RCSB PDB 1YT8 · PDBe 1YT8 · UniProt Q9I0N4

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