MolNFT v1 · #28730 · protein
Crystal structures of eap domains from staphylococcus aureus reveal an unexpected homology to bacterial superantigens
1YN5 · EAPH2: “Crystal structures of eap domains from staphylococcus aureus reveal an unexpected homology to bacterial…”. X-ray diffraction, 2 pockets (best druggability 0.40). MolNFT v1 #28730 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1YN5
- Type
- protein
- Length
- 203 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- EAPH2
- UniProt
- Q99VA9
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | EAPH2 | protein | 103 | 27% helix, 45% strand | Q99VA9 |
| B | EAPH2 | protein | 100 | 25% helix, 44% strand | Q99VA9 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.40 | 0.77 | 15 | empty |
| 2 | 74 | 0.39 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 82 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 1YN5 · Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99VA9
- Elsewhere: RCSB PDB 1YN5 · PDBe 1YN5 · UniProt Q99VA9
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