MolNFT v1 · #28702 · protein
Crystal structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfinic form
1YM9 · M-phase inducer phosphatase 2: “Crystal structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfinic…”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.51). MolNFT v1 #28702 on…
- PDB
- 1YM9
- Type
- protein
- Length
- 171 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- M-phase inducer phosphatase 2
- EC
- 3.1.3.48
- UniProt
- P30305
- Ligands
- CL
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | M-phase inducer phosphatase 2 (EC 3.1.3.48) | protein | 171 | 33% helix, 18% strand | P30305 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.51 | 0.85 | 16 | CL |
| 2 | 80 | 0.39 | 0.78 | 14 | empty |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 1YM9 · Crystal structure of the CDC25B phosphatase catalytic domain with the active site… · the same entry in another collection · chain A against A, TM-score 1.00
- P30305 · AlphaFold monomer V2.0 prediction for M-phase inducer phosphatase 2 (P30305) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30305
- Elsewhere: RCSB PDB 1YM9 · PDBe 1YM9 · UniProt P30305
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.