MolNFT v1 · #28553 · protein
Crystal structure of PAK1 kinase domain with one point mutations (K299R)
1YHW · SERINE/THREONINE-protein kinase pak 1: “Crystal structure of PAK1 kinase domain with one point mutations (K299R)”. X-ray diffraction, 1 pocket (best druggability 0.62). MolNFT v1 #28553 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1YHW
- Type
- protein
- Length
- 293 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase pak 1
- EC
- 2.7.1.37
- UniProt
- Q13153
- Pockets
- 1 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase pak 1 (EC 2.7.1.37) | protein | 293 | 43% helix, 16% strand | Q13153 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 378 | 0.62 | 0.78 | 38 | empty |
Compared structures
- 1YHW · Crystal Structure of PAK1 kinase domain with one point mutations (K299R) · the same entry in another collection · chain A against A, TM-score 1.00
- Q13153 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 1 (Q13153) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13153
- Elsewhere: RCSB PDB 1YHW · PDBe 1YHW · UniProt Q13153
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.