MolNFT v1 · #28466 · protein
Three-dimensional structure of DNA sequence specificity (S) subunit of a type I restriction-modification enzyme and its functional implications
1YF2 · Type I restriction-modification enzyme, S subunit: “Three-dimensional structure of DNA sequence specificity (S) subunit of a type I restriction-modification…”. X-ray diffraction, 8 pockets (best druggability 0.62). MolNFT v1 #28466…
- PDB
- 1YF2
- Type
- protein
- Length
- 850 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type I restriction-modification enzyme, S subunit
- UniProt
- Q57594
- Pockets
- 8 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Type I restriction-modification enzyme, S subunit | protein | 425 | 38% helix, 20% strand | Q57594 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 487 | 0.62 | 0.76 | 47 | empty |
| 2 | 203 | 0.50 | 0.76 | 29 | empty |
| 3 | 236 | 0.49 | 0.74 | 24 | empty |
| 4 | 194 | 0.48 | 0.76 | 27 | empty |
| 5 | 114 | 0.44 | 0.77 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 1017 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 1YF2 · Three-dimensional structure of DNA sequence specificity (S) subunit of a type I… · the same entry in another collection · chain A against A, TM-score 1.00
- Q57594 · AlphaFold monomer V2.0 prediction for type-1 restriction enzyme mjaxip specificity… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57594
- Elsewhere: RCSB PDB 1YF2 · PDBe 1YF2 · UniProt Q57594
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.