MolNFT v1 · #28455 · protein

Human HSP90 geldanamycin-binding domain, "closed" conformation

1YER · Heat shock protein 90: “Human HSP90 geldanamycin-binding domain, "closed" conformation”. X-ray diffraction, 1 pocket (best druggability 0.63). MolNFT v1 #28455 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YER
Type: protein
Length: 207 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heat shock protein 90
UniProt: P07900
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heat shock protein 90	protein	207	43% helix, 23% strand	P07900

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	163	0.63	0.85	26	empty

Compared structures

1YER · Human HSP90 geldanamycin-binding domain, closed" conformation" · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07900
Elsewhere: RCSB PDB 1YER · PDBe 1YER · UniProt P07900

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