MolNFT v1 · #28393 · protein

Conserved hypothetical protein pfu-1806301-001 from pyrococcus furiosus

1YCY: “Conserved hypothetical protein pfu-1806301-001 from pyrococcus furiosus”. X-ray diffraction, 3 pockets (best druggability 0.41). MolNFT v1 #28393 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YCY
Type: protein
Length: 248 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved hypothetical protein
UniProt: Q8TZN2
Pockets: 3 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 61% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Conserved hypothetical protein	protein	62	19% helix, 61% strand	Q8TZN2

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.41	0.80	16	empty
2	63	0.41	0.80	14	empty
3	59	0.40	0.80	15	empty

Interfaces

3 interfaces between chains.

A–B · 577 Å² buried · 7 hydrogen bonds · protein-protein
A–C · 561 Å² buried · 6 hydrogen bonds · protein-protein
C–D · 549 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

1YCY · Conserved hypothetical protein Pfu-1806301-001 from Pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TZN2
Elsewhere: RCSB PDB 1YCY · PDBe 1YCY · UniProt Q8TZN2

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