MolNFT v1 · #28369 · protein

CABAN33 vhh fragment against vsg

1YC7 · Anti-vsg immunoglobulin heavy chain variable domain CABAN33: “CABAN33 vhh fragment against vsg”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.52). MolNFT v1 #28369 on GenesisL1: 3D structure, binding sites and…

PDB: 1YC7
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Anti-vsg immunoglobulin heavy chain variable domain CABAN33
Ligands: SO4
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Anti-vsg immunoglobulin heavy chain variable domain CABAN33	protein	116	5% helix, 55% strand	—
B	Anti-vsg immunoglobulin heavy chain variable domain CABAN33	protein	114	5% helix, 54% strand	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	182	0.52	0.78	35	empty

Interfaces

1 interface between chains.

A–B · 511 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1YC7 · cAbAn33 VHH fragment against VSG · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1YC7 · PDBe 1YC7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.