MolNFT v1 · #28276 · RNA

HIV-1 subtype a dis RNA duplex

1Y99 · 5'- R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP…: “HIV-1 subtype a dis RNA duplex”. X-ray diffraction, 1 ligand (MG), 1 pocket (best druggability 0.65). MolNFT v1 #28276 on GenesisL1: 3D structure, binding sites and…

PDB: 1Y99
Type: RNA
Length: 46 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'- R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP *CP*AP*AP*G)-3'
Ligands: MG
Pockets: 1 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	5'- R(CPUPUPGPCPUPGPAPGPGPUPGPCPAPCPAPCPAPGP CPAPAP*G)-3'	rna	23	—	—

Ligands and binding sites

MG · Magnesium ion · metal · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	804	0.65	0.75	40	MG

Interfaces

1 interface between chains.

A–B · 1086 Å² buried · 124 hydrogen bonds · nucleic-nucleic

Compared structures

1Y99 · HIV-1 subtype A DIS RNA duplex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1Y99 · PDBe 1Y99

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.