MolNFT v1 · #27763 · protein

Crystal structure of cisk-px domain

1XTE · SERINE/THREONINE-protein kinase SGK3: “Crystal structure of cisk-px domain”. X-ray diffraction, 1 pocket (best druggability 0.33). MolNFT v1 #27763 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1XTE
Type: protein
Length: 116 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SERINE/THREONINE-protein kinase SGK3
EC: 2.7.1.37
UniProt: Q9ERE3
Pockets: 1 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein kinase SGK3 (EC 2.7.1.37)	protein	116	41% helix, 28% strand	Q9ERE3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.33	0.76	14	empty

Compared structures

1XTE · crystal structure of CISK-PX domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9ERE3 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SGK3 (Q9ERE3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ERE3
Elsewhere: RCSB PDB 1XTE · PDBe 1XTE · UniProt Q9ERE3

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