MolNFT v1 · #27567 · protein
Crystal structure of NH3-dependent NAD+ synthetase from helicobacter pylori
1XNH · NH(3)-dependent NAD(+) synthetase: “Crystal structure of NH3-dependent NAD+ synthetase from helicobacter pylori”. X-ray diffraction, 3 pockets (best druggability 0.79). MolNFT v1 #27567 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1XNH
- Type
- protein
- Length
- 251 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NH(3)-dependent NAD(+) synthetase
- EC
- 6.3.1.5
- UniProt
- O25096
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NH(3)-dependent NAD(+) synthetase (EC 6.3.1.5) | protein | 251 | 55% helix, 6% strand | O25096 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 497 | 0.79 | 0.86 | 70 | empty |
| 2 | 131 | 0.44 | 0.76 | 19 | empty |
| 3 | 54 | 0.28 | 0.74 | 13 | empty |
Compared structures
- 1XNH · Crystal Structure of NH3-dependent NAD+ synthetase from Helicobacter pylori · the same entry in another collection · chain A against A, TM-score 1.00
- O25096 · AlphaFold monomer V2.0 prediction for NH(3)-dependent NAD(+) synthetase (O25096) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O25096
- Elsewhere: RCSB PDB 1XNH · PDBe 1XNH · UniProt O25096
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