MolNFT v1 · #27546 · protein
CD3 epsilon and delta ectodomain fragment complex in single-chain construct
1XMW · Chimeric CD3 mouse epsilon and sheep delta ectodomain…: “CD3 epsilon and delta ectodomain fragment complex in single-chain construct”. Solution nmr, 2 pockets (best druggability 0.39). MolNFT v1 #27546 on GenesisL1: 3D structure…
- PDB
- 1XMW
- Type
- protein
- Length
- 178 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chimeric CD3 mouse epsilon and sheep delta ectodomain fragment complex
- UniProt
- P22646, P18438
- Pockets
- 2 · best druggability 0.39
Structure
solution nmr · 1 distinct chain · 2% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chimeric CD3 mouse epsilon and sheep delta ectodomain fragment complex | protein | 178 | 2% helix, 35% strand | P22646, P18438 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 127 | 0.39 | 0.74 | 18 | empty |
| 2 | 64 | 0.36 | 0.78 | 20 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1XMW · CD3 epsilon and delta ectodomain fragment complex in single-chain construct · the same entry in another collection · chain A against A, TM-score 1.00
- P22646 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD3 epsilon chain… · a predicted model of the same protein · chain A against A, TM-score 0.41
- P18438 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD3 delta chain (P18438) · a predicted model of the same protein · chain A against A, TM-score 0.35
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22646
- Every structure of UniProt P18438
- Elsewhere: RCSB PDB 1XMW · PDBe 1XMW · UniProt P22646 · UniProt P18438
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