MolNFT v1 · #27463 · protein

Bacterial luciferase BETA2 homodimer

1XKJ · BETA2 luciferase: “Bacterial luciferase BETA2 homodimer”. X-ray diffraction, 12 pockets (best druggability 0.66). MolNFT v1 #27463 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1XKJ
Type: protein
Length: 648 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BETA2 luciferase
EC: 1.14.14.3
UniProt: P07739
Pockets: 12 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	BETA2 luciferase (EC 1.14.14.3)	protein	324	47% helix, 17% strand	P07739

Pockets

12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	176	0.66	0.86	32	empty
2	147	0.65	0.87	32	empty
3	164	0.62	0.84	19	empty
4	177	0.60	0.82	20	empty
5	193	0.55	0.79	26	empty

Interfaces

1 interface between chains.

A–B · 1896 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

1XKJ · Bacterial luciferase BETA2 homodimer · the same entry in another collection · chain A against A, TM-score 1.00
P07739 · AlphaFold monomer V2.0 prediction for alkanal monooxygenase beta chain (P07739) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07739
Elsewhere: RCSB PDB 1XKJ · PDBe 1XKJ · UniProt P07739

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