MolNFT v1 · #27413 · protein

Co-bound structure of bjfixlh

1XJ2 · Sensor protein fixl: “Co-bound structure of bjfixlh”. X-ray diffraction, 2 ligands (HEM, CMO), 1 pocket (best druggability 0.78). MolNFT v1 #27413 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1XJ2
Type: protein
Length: 116 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sensor protein fixl
EC: 2.7.3.-
UniProt: P23222
Ligands: HEM, CMO
Pockets: 1 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sensor protein fixl (EC 2.7.3.-)	protein	116	36% helix, 34% strand	P23222

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A
CMO · Carbon monoxide · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	332	0.78	0.88	30	HEM, CMO

Compared structures

1XJ2 · CO-bound structure of bjFixLH · the same entry in another collection · chain A against A, TM-score 1.00
P23222 · AlphaFold monomer V2.0 prediction for sensor protein fixl (P23222) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23222
Elsewhere: RCSB PDB 1XJ2 · PDBe 1XJ2 · UniProt P23222

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