MolNFT v1 · #27383 · protein

Extragenic suppressor from pyrococcus furiosus pfu-1862794-001

1XI6: “Extragenic suppressor from pyrococcus furiosus pfu-1862794-001”. X-ray diffraction, 2 pockets (best druggability 0.45). MolNFT v1 #27383 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1XI6
Type: protein
Length: 234 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Extragenic suppressor
UniProt: Q8TZH9
Pockets: 2 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Extragenic suppressor	protein	234	34% helix, 30% strand	Q8TZH9

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	154	0.45	0.76	23	empty
2	54	0.28	0.74	13	empty

Compared structures

1XI6 · Extragenic suppressor from Pyrococcus furiosus Pfu-1862794-001 · the same entry in another collection · chain A against A, TM-score 1.00
Q8TZH9 · AlphaFold monomer V2.0 prediction for fructose-1,6-bisphosphatase (Q8TZH9) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TZH9
Elsewhere: RCSB PDB 1XI6 · PDBe 1XI6 · UniProt Q8TZH9

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