MolNFT v1 · #27335 · protein
Methionine aminopeptidase from hyperthermophile pyrococcus furiosus
1XGO: “Methionine aminopeptidase from hyperthermophile pyrococcus furiosus”. X-ray diffraction, 4 pockets (best druggability 0.64). MolNFT v1 #27335 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1XGO
- Type
- protein
- Length
- 295 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Methionine aminopeptidase
- EC
- 3.4.11.18
- UniProt
- P56218
- Pockets
- 4 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Methionine aminopeptidase (EC 3.4.11.18) | protein | 295 | 32% helix, 22% strand | P56218 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 156 | 0.64 | 0.85 | 28 | empty |
| 2 | 89 | 0.37 | 0.75 | 19 | empty |
| 3 | 104 | 0.37 | 0.74 | 21 | empty |
| 4 | 59 | 0.32 | 0.76 | 11 | empty |
Compared structures
- 1XGO · Methionine aminopeptidase from hyperthermophile pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00
- P56218 · AlphaFold monomer V2.0 prediction for methionine aminopeptidase (P56218) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56218
- Elsewhere: RCSB PDB 1XGO · PDBe 1XGO · UniProt P56218
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