MolNFT v1 · #27275 · protein
Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of smc atpases.
1XEW · Smc protein: “Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of smc atpases.”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #27275 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1XEW
- Type
- protein
- Length
- 307 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Smc protein
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Smc protein | protein | 147 | 26% helix, 31% strand | — |
| Y | Smc protein | protein | 160 | 49% helix, 22% strand | — |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.53 | 0.81 | 16 | empty |
| 2 | 69 | 0.39 | 0.79 | 15 | empty |
| 3 | 64 | 0.31 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- X–Y · 2714 Ų buried · 40 hydrogen bonds · protein-protein
Compared structures
- 1XEW · Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC… · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1XEW · PDBe 1XEW
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.