MolNFT v1 · #27113 · protein
Solution structure of dimeric SAM domain from mapkkk STE11
1X9X · SERINE/THREONINE-protein kinase STE11: “Solution structure of dimeric SAM domain from mapkkk STE11”. Solution nmr, 1 pocket (best druggability 0.43). MolNFT v1 #27113 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1X9X
- Type
- protein
- Length
- 124 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SERINE/THREONINE-protein kinase STE11
- EC
- 2.7.1.37
- UniProt
- P23561
- Pockets
- 1 · best druggability 0.43
Structure
solution nmr · 1 distinct chain · 63% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | SERINE/THREONINE-protein kinase STE11 (EC 2.7.1.37) | protein | 62 | 63% helix, 0% strand | P23561 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.43 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 534 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 1X9X · Solution Structure of Dimeric SAM Domain from MAPKKK Ste11 · the same entry in another collection · chain A against A, TM-score 1.00
- P23561 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase STE11 (P23561) · a predicted model of the same protein · chain A against A, TM-score 0.81
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23561
- Elsewhere: RCSB PDB 1X9X · PDBe 1X9X · UniProt P23561
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