MolNFT v1 · #27060 · protein

Crystal structure of apo-KDO8P synthase

1X8F · 2-dehydro-3-deoxyphosphooctonate aldolase: “Crystal structure of apo-KDO8P synthase”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #27060 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1X8F
Type: protein
Length: 272 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 2-dehydro-3-deoxyphosphooctonate aldolase
EC: 2.5.1.55
UniProt: P0A715
Pockets: 2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	2-dehydro-3-deoxyphosphooctonate aldolase (EC 2.5.1.55)	protein	272	39% helix, 17% strand	P0A715

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	406	0.67	0.80	44	empty
2	61	0.27	0.73	17	empty

Compared structures

1X8F · Crystal Structure Of apo-Kdo8P Synthase · the same entry in another collection · chain A against A, TM-score 1.00
P0A715 · AlphaFold monomer V2.0 prediction for 2-dehydro-3-deoxyphosphooctonate aldolase (P0A715) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A715
Elsewhere: RCSB PDB 1X8F · PDBe 1X8F · UniProt P0A715

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.