MolNFT v1 · #26949 · protein

Solution structure of the C-terminal gal-bind lectin domain from human galectin-4

1X50: “Solution structure of the C-terminal gal-bind lectin domain from human galectin-4”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #26949 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1X50
Type: protein
Length: 164 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Galectin-4
UniProt: P56470
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 3% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Galectin-4	protein	164	3% helix, 41% strand	P56470

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.33	0.77	16	empty

Compared structures

1X50 · Solution structure of the C-terminal gal-bind lectin domain from human galectin-4 · the same entry in another collection · chain A against A, TM-score 1.00
P56470 · AlphaFold monomer V2.0 prediction for galectin-4 (P56470) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56470
Elsewhere: RCSB PDB 1X50 · PDBe 1X50 · UniProt P56470

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