MolNFT v1 · #26939 · protein

Solution structure of pwi domain in U4/U6 small nuclear ribonucleoprotein PRP3(HPRP3)

1X4Q: “Solution structure of pwi domain in U4/U6 small nuclear ribonucleoprotein PRP3(HPRP3)”. Solution nmr, 1 pocket (best druggability 0.45). MolNFT v1 #26939 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1X4Q
Type: protein
Length: 92 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U4/U6 small nuclear ribonucleoprotein PRP3
UniProt: O43395
Pockets: 1 · best druggability 0.45

Structure

solution nmr · 1 distinct chain · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	U4/U6 small nuclear ribonucleoprotein PRP3	protein	92	61% helix, 0% strand	O43395

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	175	0.45	0.75	27	empty

Compared structures

1X4Q · Solution structure of PWI domain in U4/U6 small nuclear ribonucleoprotein Prp3(hPrp3) · the same entry in another collection · chain A against A, TM-score 1.00
O43395 · AlphaFold monomer V2.0 prediction for U4/U6 small nuclear ribonucleoprotein PRP3 (O43395) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43395
Elsewhere: RCSB PDB 1X4Q · PDBe 1X4Q · UniProt O43395

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