MolNFT v1 · #26788 · protein

Crystal structure of family 30 carbohydrate binding module.

1WZX · COG3291: fog: pkd repeat: “Crystal structure of family 30 carbohydrate binding module.”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #26788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WZX
Type: protein
Length: 695 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: COG3291: fog: pkd repeat
Pockets: 4 · best druggability 0.67

Structure

x-ray diffraction · 3 distinct chains · 6% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	COG3291: fog: pkd repeat	protein	175	7% helix, 34% strand	—
B	COG3291: fog: pkd repeat	protein	174	6% helix, 38% strand	—
C, D	COG3291: fog: pkd repeat	protein	173	6% helix, 39% strand	—

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	420	0.67	0.79	32	empty
2	472	0.66	0.78	56	empty
3	90	0.45	0.81	25	empty
4	59	0.33	0.77	16	empty

Interfaces

4 interfaces between chains.

B–D · 340 Å² buried · 1 hydrogen bond · protein-protein
A–C · 339 Å² buried · 0 hydrogen bonds · protein-protein
A–B · 302 Å² buried · 4 hydrogen bonds · protein-protein
B–C · 50 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1WZX · Crystal Structure of Family 30 Carbohydrate Binding Module. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1WZX · PDBe 1WZX

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