MolNFT v1 · #26759 · protein

The crystal structure of the P130CAS SH3 domain at 1.1 a resolution

1WYX · Crk-associated substrate: “The crystal structure of the P130CAS SH3 domain at 1.1 a resolution”. X-ray diffraction, 1 ligand (MG). MolNFT v1 #26759 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WYX
Type: protein
Length: 137 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Crk-associated substrate
UniProt: P56945
Ligands: MG

Structure

x-ray diffraction · 2 distinct chains · 9% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Crk-associated substrate	protein	68	9% helix, 53% strand	P56945
B	Crk-associated substrate	protein	69	9% helix, 55% strand	P56945

Ligands and binding sites

MG · Magnesium ion · metal · chains A, B
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 411 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

1WYX · The Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution · the same entry in another collection · chain A against A, TM-score 1.00
P56945 · AlphaFold monomer V2.0 prediction for breast cancer anti-estrogen resistance protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56945
Elsewhere: RCSB PDB 1WYX · PDBe 1WYX · UniProt P56945

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