MolNFT v1 · #26747 · protein

Solution structure of the ch domain of human NEDD9 interacting protein with calponin homology and lim domains

1WYL: “Solution structure of the ch domain of human NEDD9 interacting protein with calponin homology and lim domains”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #26747 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 1WYL
Type: protein
Length: 116 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NEDD9 interacting protein with calponin homology and lim domains
UniProt: Q8TDZ2
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain · 55% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NEDD9 interacting protein with calponin homology and lim domains	protein	116	55% helix, 0% strand	Q8TDZ2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.31	0.76	15	empty

Compared structures

1WYL · Solution structure of the CH domain of human NEDD9 interacting protein with calponin… · the same entry in another collection · chain A against A, TM-score 1.00
Q8TDZ2 · AlphaFold monomer V2.0 prediction for [F-actin]-monooxygenase MICAL1 (Q8TDZ2) · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TDZ2
Elsewhere: RCSB PDB 1WYL · PDBe 1WYL · UniProt Q8TDZ2

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