MolNFT v1 · #26712 · protein
Crystal structure of tryptophan synthase a-subunit with indole-3- propanol phosphate from thermus thermophilus HB8
1WXJ · Tryptophan synthase alpha chain: “Crystal structure of tryptophan synthase a-subunit with indole-3- propanol phosphate from thermus…”. X-ray diffraction, 2 ligands (IPL, SO4), 1 pocket (best druggability 0.54). MolNFT v1 #26712 on…
- PDB
- 1WXJ
- Type
- protein
- Length
- 239 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tryptophan synthase alpha chain
- EC
- 4.2.1.20
- UniProt
- P16608
- Ligands
- IPL, SO4
- Pockets
- 1 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tryptophan synthase alpha chain (EC 4.2.1.20) | protein | 239 | 49% helix, 15% strand | P16608 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 213 | 0.54 | 0.77 | 29 | IPL |
Compared structures
- 1WXJ · Crystal Structure Of Tryptophan Synthase A-Subunit with Indole-3-propanol phosphate From… · the same entry in another collection · chain A against A, TM-score 1.00
- P16608 · AlphaFold monomer V2.0 prediction for tryptophan synthase alpha chain (P16608) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16608
- Elsewhere: RCSB PDB 1WXJ · PDBe 1WXJ · UniProt P16608
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.