MolNFT v1 · #26604 · protein
E. COLI recq hrdc domain
1WUD · ATP-dependent DNA helicase recq: “E. COLI recq hrdc domain”. X-ray diffraction, 3 pockets (best druggability 0.53). MolNFT v1 #26604 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1WUD
- Type
- protein
- Length
- 229 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP-dependent DNA helicase recq
- EC
- 3.6.1.-
- UniProt
- P15043
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATP-dependent DNA helicase recq (EC 3.6.1.-) | protein | 77 | 73% helix, 0% strand | P15043 |
| B, D | ATP-dependent DNA helicase recq (EC 3.6.1.-) | protein | 76 | 74% helix, 0% strand | P15043 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 210 | 0.53 | 0.77 | 19 | empty |
| 2 | 88 | 0.41 | 0.78 | 22 | empty |
| 3 | 72 | 0.37 | 0.78 | 20 | empty |
Interfaces
2 interfaces between chains.
- A–D · 625 Ų buried · 8 hydrogen bonds · protein-protein
- B–D · 510 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 15 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15043
- Elsewhere: RCSB PDB 1WUD · PDBe 1WUD · UniProt P15043
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.