MolNFT v1 · #26566 · protein

Solution structure of butx-mtx: a butantoxin-maurotoxin chimera

1WT7: “Solution structure of butx-mtx: a butantoxin-maurotoxin chimera”. Solution nmr, 1 pocket (best druggability 0.29). MolNFT v1 #26566 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WT7
Type: protein
Length: 41 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Butx-mtx
UniProt: P59936, P80719
Pockets: 1 · best druggability 0.29

Structure

solution nmr · 1 distinct chain · 29% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Butx-mtx	protein	41	29% helix, 20% strand	P59936, P80719

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.29	0.74	15	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1WT7 · Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera · the same entry in another collection · chain A against A, TM-score 1.00
P59936 · AlphaFold monomer V2.0 prediction for potassium channel toxin alpha- ktx 12.1 (P59936) · a predicted model of the same protein · chain A against A, TM-score 0.61
P80719 · AlphaFold monomer V2.0 prediction for potassium channel toxin alpha- ktx 6.2 (P80719) · a predicted model of the same protein · chain A against A, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P59936
Every structure of UniProt P80719
Elsewhere: RCSB PDB 1WT7 · PDBe 1WT7 · UniProt P59936 · UniProt P80719

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