MolNFT v1 · #26291 · protein

Terminal flower 1 (TFL1) from arabidopsis thaliana

1WKO · Terminal flower 1 protein: “Terminal flower 1 (TFL1) from arabidopsis thaliana”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #26291 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WKO
Type: protein
Length: 330 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Terminal flower 1 protein
UniProt: P93003
Pockets: 4 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Terminal flower 1 protein	protein	165	14% helix, 35% strand	P93003

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	237	0.53	0.76	29	empty
2	58	0.38	0.79	19	empty
3	64	0.37	0.78	15	empty
4	63	0.35	0.77	16	empty

Interfaces

1 interface between chains.

A–B · 362 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

1WKO · Terminal flower 1 (tfl1) from arabidopsis thaliana · the same entry in another collection · chain A against A, TM-score 1.00
P93003 · AlphaFold monomer V2.0 prediction for protein terminal flower 1 (P93003) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P93003
Elsewhere: RCSB PDB 1WKO · PDBe 1WKO · UniProt P93003

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