MolNFT v1 · #26240 · protein

Solution structure of phosphotyrosine interaction domain of mouse numb protein

1WJ1: “Solution structure of phosphotyrosine interaction domain of mouse numb protein”. Solution nmr, 1 pocket (best druggability 0.42). MolNFT v1 #26240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WJ1
Type: protein
Length: 156 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Numb protein
UniProt: Q9QZS3
Pockets: 1 · best druggability 0.42

Structure

solution nmr · 1 distinct chain · 28% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Numb protein	protein	156	28% helix, 31% strand	Q9QZS3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	130	0.42	0.76	21	empty

Compared structures

1WJ1 · Solution structure of phosphotyrosine interaction domain of mouse Numb protein · the same entry in another collection · chain A against A, TM-score 1.00
Q9QZS3 · AlphaFold monomer V2.0 prediction for protein numb homolog (Q9QZS3) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9QZS3
Elsewhere: RCSB PDB 1WJ1 · PDBe 1WJ1 · UniProt Q9QZS3

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