MolNFT v1 · #26120 · protein

The first C2 domain of human synaptotagmin xiii

1WFM: “The first C2 domain of human synaptotagmin xiii”. Solution nmr, 1 pocket (best druggability 0.66). MolNFT v1 #26120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WFM
Type: protein
Length: 138 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Synaptotagmin xiii
UniProt: Q7L8C5
Pockets: 1 · best druggability 0.66

Structure

solution nmr · 1 distinct chain · 0% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Synaptotagmin xiii	protein	138	0% helix, 42% strand	Q7L8C5

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	358	0.66	0.80	36	empty

Compared structures

1WFM · The first C2 domain of human synaptotagmin XIII · the same entry in another collection · chain A against A, TM-score 1.00
Q7L8C5 · AlphaFold monomer V2.0 prediction for synaptotagmin-13 (Q7L8C5) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7L8C5
Elsewhere: RCSB PDB 1WFM · PDBe 1WFM · UniProt Q7L8C5

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