MolNFT v1 · #26014 · protein
Crystal structure of the T13 ibdv viral particle reveals a missing link in icosahedral viruses evolution
1WCE · Major structural protein VP2: “Crystal structure of the T13 ibdv viral particle reveals a missing link in icosahedral viruses evolution”. X-ray diffraction, 20 pockets (best druggability 0.48). MolNFT v1 #26014 on GenesisL1: 3D…
- PDB
- 1WCE
- Type
- protein
- Length
- 5,533 residues
- Chains
- 13
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major structural protein VP2
- UniProt
- P15480
- Pockets
- 20 · best druggability 0.48
Structure
x-ray diffraction · 11 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major structural protein VP2 | protein | 425 | 0% helix, 0% strand | P15480 |
| B, C | Major structural protein VP2 | protein | 430 | 0% helix, 0% strand | P15480 |
| D | Major structural protein VP2 | protein | 424 | 0% helix, 0% strand | P15480 |
| E, L | Major structural protein VP2 | protein | 429 | 0% helix, 0% strand | P15480 |
| F | Major structural protein VP2 | protein | 436 | 0% helix, 0% strand | P15480 |
| G | Major structural protein VP2 | protein | 426 | 0% helix, 0% strand | P15480 |
| H | Major structural protein VP2 | protein | 423 | 0% helix, 0% strand | P15480 |
| I | Major structural protein VP2 | protein | 417 | 0% helix, 0% strand | P15480 |
| J | Major structural protein VP2 | protein | 423 | 0% helix, 0% strand | P15480 |
| K | Major structural protein VP2 | protein | 416 | 0% helix, 0% strand | P15480 |
| M | Major structural protein VP2 | protein | 425 | 0% helix, 0% strand | P15480 |
Pockets
20 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 220 | 0.48 | 0.72 | 53 | empty |
| 2 | 222 | 0.48 | 0.72 | 48 | empty |
| 3 | 193 | 0.47 | 0.73 | 50 | empty |
| 4 | 184 | 0.46 | 0.73 | 36 | empty |
| 5 | 173 | 0.46 | 0.73 | 46 | empty |
Interfaces
21 interfaces between chains.
- D–M · 461 Ų buried · 0 hydrogen bonds · protein-protein
- G–K · 461 Ų buried · 0 hydrogen bonds · protein-protein
- H–L · 459 Ų buried · 0 hydrogen bonds · protein-protein
- A–J · 459 Ų buried · 0 hydrogen bonds · protein-protein
- B–K · 459 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1WCE · Crystal structure of the T13 IBDV viral particle reveals a missing link in icosahedral… · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15480
- Elsewhere: RCSB PDB 1WCE · PDBe 1WCE · UniProt P15480
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