MolNFT v1 · #25953 · protein
3-isopropylmalate dehydrogenase (ipmdh) mutant (M219A)FROM thermus thermophilus
1WAL · Protein (3-isopropylmalate dehydrogenase): “3-isopropylmalate dehydrogenase (ipmdh) mutant (M219A)FROM thermus thermophilus”. X-ray diffraction, 2 pockets (best druggability 0.68). MolNFT v1 #25953 on GenesisL1: 3D structure…
- PDB
- 1WAL
- Type
- protein
- Length
- 345 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (3-isopropylmalate dehydrogenase)
- UniProt
- P61495
- Pockets
- 2 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 50% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (3-isopropylmalate dehydrogenase) | protein | 345 | 50% helix, 18% strand | P61495 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 67 | 0.68 | 0.95 | 18 | empty |
| 2 | 243 | 0.54 | 0.77 | 32 | empty |
Compared structures
- 1WAL · 3-isopropylmalate dehydrogenase (ipmdh) mutant (M219A)FROM thermus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
- P61495 · AlphaFold monomer V2.0 prediction for 3-isopropylmalate dehydrogenase (P61495) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61495
- Elsewhere: RCSB PDB 1WAL · PDBe 1WAL · UniProt P61495
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.