MolNFT v1 · #25939 · protein

Crystal structure of the M131F L135A evad double mutant

1WA4 · PCZA361.16: “Crystal structure of the M131F L135A evad double mutant”. X-ray diffraction, 1 pocket (best druggability 0.55). MolNFT v1 #25939 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1WA4
Type: protein
Length: 205 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PCZA361.16
UniProt: O52806
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PCZA361.16	protein	205	14% helix, 37% strand	O52806

Ligands and binding sites

GOL · Glycerol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.55	0.81	26	empty

Compared structures

1WA4 · Crystal structure of the M131F L135A EvaD double mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O52806
Elsewhere: RCSB PDB 1WA4 · PDBe 1WA4 · UniProt O52806

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