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MolNFT v1 · #2567 · protein

Active site S19A mutant of bovine heart phosphotyrosyl phosphatase

1C0E · Protein (tyrosine phosphatase (orthophosphoric monoester…: “Active site S19A mutant of bovine heart phosphotyrosyl phosphatase”. X-ray diffraction, 1 ligand (PO4). MolNFT v1 #2567 on GenesisL1: 3D structure, binding sites and…

PDB
1C0E
Type
protein
Length
308 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein (tyrosine phosphatase (orthophosphoric monoester phosphohydrolase))
EC
3.1.3.2
UniProt
P11064
Ligands
PO4

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BProtein (tyrosine phosphatase (orthophosphoric monoester phosphohydrolase)) (EC 3.1.3.2)protein15442% helix, 15% strandP11064

Ligands and binding sites

  • PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 598 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

  • 1C0E · Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase · the same entry in another collection · chain A against A, TM-score 1.00
  • P11064 · AlphaFold monomer V2.0 prediction for low molecular weight phosphotyrosine protein… · a predicted model of the same protein · chain A against A, TM-score 0.99

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