MolNFT v1 · #25611 · protein
Arabidopsis thaliana mitochondrial kas
1W0I · 3-oxoacyl carrier protein synthase: “Arabidopsis thaliana mitochondrial kas”. X-ray diffraction, 2 ligands (K, SO4), 7 pockets (best druggability 0.72). MolNFT v1 #25611 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1W0I
- Type
- protein
- Length
- 862 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-oxoacyl carrier protein synthase
- EC
- 2.3.1.41
- UniProt
- Q8L3X9
- Ligands
- K, SO4
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 3-oxoacyl carrier protein synthase (EC 2.3.1.41) | protein | 431 | 39% helix, 21% strand | Q8L3X9 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 227 | 0.72 | 0.87 | 40 | empty |
| 2 | 263 | 0.71 | 0.86 | 38 | empty |
| 3 | 124 | 0.44 | 0.77 | 26 | empty |
| 4 | 141 | 0.43 | 0.75 | 19 | empty |
| 5 | 82 | 0.38 | 0.77 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 3452 Ų buried · 41 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8L3X9
- Elsewhere: RCSB PDB 1W0I · PDBe 1W0I · UniProt Q8L3X9
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