MolNFT v1 · #25301 · protein

Crystal structure of alanine dehydrogenase (AF1665) from archaeoglobus fulgidus at 2.80 a resolution

1VLL: “Crystal structure of alanine dehydrogenase (AF1665) from archaeoglobus fulgidus at 2.80 a resolution”. X-ray diffraction, 2 pockets (best druggability 0.70). MolNFT v1 #25301 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1VLL
Type: protein
Length: 642 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alanine dehydrogenase
EC: 1.4.1.1
UniProt: O28608
Pockets: 2 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Alanine dehydrogenase (EC 1.4.1.1)	protein	321	36% helix, 26% strand	O28608

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	568	0.70	0.79	54	empty
2	482	0.67	0.79	41	empty

Interfaces

1 interface between chains.

A–B · 2024 Å² buried · 22 hydrogen bonds · protein-protein

Compared structures

1VLL · Crystal structure of alanine dehydrogenase (AF1665) from Archaeoglobus fulgidus at 2.80 A… · the same entry in another collection · chain A against A, TM-score 1.00
O28608 · AlphaFold monomer V2.0 prediction for alanine dehydrogenase (O28608) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O28608
Elsewhere: RCSB PDB 1VLL · PDBe 1VLL · UniProt O28608

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