MolNFT v1 · #25245 · protein

Crystal structure of ubiquitin carboxyl-terminal hydrolase 6 (YFR010W) from saccharomyces cerevisiae at 1.74 a resolution

1VJV: “Crystal structure of ubiquitin carboxyl-terminal hydrolase 6 (YFR010W) from saccharomyces cerevisiae at 1.74…”. X-ray diffraction, 4 pockets (best druggability 0.66). MolNFT v1 #25245 on GenesisL1: 3D structure, binding sites and…

PDB: 1VJV
Type: protein
Length: 367 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin carboxyl-terminal hydrolase 6
EC: 3.1.2.15
UniProt: P43593
Pockets: 4 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15)	protein	367	39% helix, 27% strand	P43593

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	245	0.66	0.83	26	empty
2	204	0.55	0.79	24	empty
3	86	0.43	0.79	21	empty
4	96	0.35	0.74	20	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

1VJV · Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces… · the same entry in another collection · chain A against A, TM-score 1.00
P43593 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 6 (P43593) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43593
Elsewhere: RCSB PDB 1VJV · PDBe 1VJV · UniProt P43593

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