MolNFT v1 · #25242 · protein

Structure of alpha-amylase precursor

1VJS: “Structure of alpha-amylase precursor”. X-ray diffraction, 3 pockets (best druggability 0.57). MolNFT v1 #25242 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1VJS
Type: protein
Length: 469 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-amylase
EC: 3.2.1.1
UniProt: P06278
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-amylase (EC 3.2.1.1)	protein	469	29% helix, 23% strand	P06278

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	400	0.57	0.75	39	empty
2	55	0.40	0.82	15	empty
3	54	0.25	0.73	21	empty

Compared structures

1VJS · Structure of alpha-amylase precursor · the same entry in another collection · chain A against A, TM-score 1.00
P06278 · AlphaFold monomer V2.0 prediction for alpha-amylase (P06278) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06278
Elsewhere: RCSB PDB 1VJS · PDBe 1VJS · UniProt P06278

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