MolNFT v1 · #25219 · protein

Crystal structure of a novel family of manganese-containing cupin (TM1459) from thermotoga maritima at 1.65 a resolution

1VJ2 · Novel manganese-containing cupin TM1459: “Crystal structure of a novel family of manganese-containing cupin (TM1459) from thermotoga maritima at 1.65 a…”. X-ray diffraction, 2 ligands (UNL, MN), 3 pockets (best druggability 0.49).…

PDB: 1VJ2
Type: protein
Length: 228 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Novel manganese-containing cupin TM1459
UniProt: Q9X1H0
Ligands: UNL, MN
Pockets: 3 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 60% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Novel manganese-containing cupin TM1459	protein	114	5% helix, 60% strand	Q9X1H0

Ligands and binding sites

UNL · Unknown ligand · ligand · chains A
MN · Manganese (II) ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.49	0.78	23	UNL
2	96	0.47	0.80	22	empty
3	118	0.39	0.74	21	empty

Interfaces

1 interface between chains.

A–B · 1795 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

1VJ2 · Crystal structure of a novel family of manganese-containing cupin (tm1459) from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X1H0
Elsewhere: RCSB PDB 1VJ2 · PDBe 1VJ2 · UniProt Q9X1H0

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