MolNFT v1 · #25153 · protein

Crystal structure of a flagellar protein

1VH6 · Flagellar protein flis: “Crystal structure of a flagellar protein”. X-ray diffraction, 2 pockets (best druggability 0.66). MolNFT v1 #25153 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1VH6
Type: protein
Length: 210 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flagellar protein flis
UniProt: P39739
Pockets: 2 · best druggability 0.66

Structure

x-ray diffraction · 2 distinct chains · 88% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flagellar protein flis	protein	102	88% helix, 0% strand	P39739
B	Flagellar protein flis	protein	108	87% helix, 0% strand	P39739

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.66	0.91	24	empty
2	55	0.28	0.73	12	empty

Interfaces

1 interface between chains.

A–B · 3103 Å² buried · 26 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

1VH6 · Crystal structure of a flagellar protein · the same entry in another collection · chain A against A, TM-score 1.00
P39739 · AlphaFold monomer V2.0 prediction for flagellar secretion chaperone flis (P39739) · a predicted model of the same protein · chain A against A, TM-score 0.50

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39739
Elsewhere: RCSB PDB 1VH6 · PDBe 1VH6 · UniProt P39739

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