MolNFT v1 · #25131 · protein

Crystal structure of 2'-5' RNA ligase from pyrococcus horikoshii

1VGJ · Hypothetical protein PH0099: “Crystal structure of 2'-5' RNA ligase from pyrococcus horikoshii”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #25131 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1VGJ
Type: protein
Length: 184 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein PH0099
UniProt: O57823
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein PH0099	protein	184	31% helix, 44% strand	O57823

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	281	0.54	0.76	30	empty

Modifications

Observed in the structure: 3 modified (engineered).

Compared structures

1VGJ · Crystal structure of 2'-5' RNA ligase from Pyrococcus horikoshii · the same entry in another collection · chain A against A, TM-score 1.00
O57823 · AlphaFold monomer V2.0 prediction for RNA 2',3'-cyclic phosphodiesterase (O57823) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O57823
Elsewhere: RCSB PDB 1VGJ · PDBe 1VGJ · UniProt O57823

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