MolNFT v1 · #25120 · protein
Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic thermotoga maritima F132A/L128A/I123A mutant
1VG6 · Octoprenyl-diphosphate synthase: “Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic thermotoga maritima…”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #25120 on GenesisL1: 3D…
- PDB
- 1VG6
- Type
- protein
- Length
- 279 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Octoprenyl-diphosphate synthase
- EC
- 2.5.1.11
- UniProt
- Q9X1M1
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Octoprenyl-diphosphate synthase (EC 2.5.1.11) | protein | 279 | 74% helix, 1% strand | Q9X1M1 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 512 | 0.70 | 0.80 | 57 | empty |
| 2 | 63 | 0.68 | 0.95 | 22 | empty |
| 3 | 162 | 0.50 | 0.77 | 15 | empty |
| 4 | 55 | 0.28 | 0.74 | 16 | empty |
Compared structures
- 1VG6 · Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X1M1
- Elsewhere: RCSB PDB 1VG6 · PDBe 1VG6 · UniProt Q9X1M1
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