MolNFT v1 · #25117 · protein

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic thermotoga maritima A76Y/S77F mutant

1VG3 · Octoprenyl-diphosphate synthase: “Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic thermotoga maritima A76Y/S77F…”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.73). MolNFT v1 #25117…

PDB: 1VG3
Type: protein
Length: 279 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Octoprenyl-diphosphate synthase
EC: 2.5.1.11
UniProt: Q9X1M1
Ligands: SO4
Pockets: 2 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 75% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Octoprenyl-diphosphate synthase (EC 2.5.1.11)	protein	279	75% helix, 2% strand	Q9X1M1

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	433	0.73	0.83	50	SO4
2	164	0.50	0.77	19	empty

Compared structures

1VG3 · Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X1M1
Elsewhere: RCSB PDB 1VG3 · PDBe 1VG3 · UniProt Q9X1M1

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