MolNFT v1 · #2490 · protein

Fhua from E. COLI

1BY3 · Protein (ferrichrome-iron receptor precursor (fhua)): “Fhua from E. COLI”. X-ray diffraction, 1 ligand (OES), 6 pockets (best druggability 0.87). MolNFT v1 #2490 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1BY3
Type: protein
Length: 695 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (ferrichrome-iron receptor precursor (fhua))
UniProt: P06971
Ligands: OES
Pockets: 6 · best druggability 0.87

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 56% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (ferrichrome-iron receptor precursor (fhua))	protein	695	6% helix, 56% strand	P06971

Ligands and binding sites

OES · N-octyl-2-hydroxyethyl sulfoxide · ligand · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1200	0.87	0.88	171	empty
2	65	0.73	0.98	24	empty
3	173	0.69	0.88	34	empty
4	110	0.63	0.88	28	OES
5	413	0.63	0.78	43	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1BY3 · Fhua from E. COLI · the same entry in another collection · chain A against A, TM-score 1.00
P06971 · AlphaFold monomer V2.0 prediction for ferrichrome outer membrane TRANSPORTER/PHAGE… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06971
Elsewhere: RCSB PDB 1BY3 · PDBe 1BY3 · UniProt P06971

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.